GUIDE (Growing Up In Digital Europe: EuroCohort) will be Europe’s first comparative birth cohort survey: a Research Infrastructure that will be an important source of high quality longitudinal statistical evidence to support the development of social policies which will enhance the wellbeing of children, young people and their families across Europe for many years to come. GUIDE/EuroCohort will be an accelerated cohort survey including a sample of new born infants as well as a sample of school age children.